Angel di Maria says he was unable to settle at Manchester United because his position kept changing under boss Louis van Gaal.The Argentinian joined United from Real Madrid for a British record £59.7million in 2014 but left for Paris St Germain in August – and he has no regrets about the move.Di Maria told BBC1’s Football Focus: “It’s more that they didn’t let me settle properly than I couldn’t settle.“I started a game in one position then the next game in another. I scored goals playing in one position, then the next game I was picked to play in a different postion. I don’t think this helped me settle.“It’s up to the manager to decide but I think the player should be comfortable in that position and adapt to it.“I left and that team are still playing the same way. Out of the European competitions, far from being champions of the Premier League.“I don’t think it was my fault, or the fault of my team-mates. Every time I was given the opportunity I did all I could but it didn’t work out as I hoped.“So I decided to leave, not only to he happy but to win things. That’s what I’m doing here.”PSG have already wrapped up the Ligue 1 title and are looking forward to a Champions League quarter-final against Manchester City.“I’m very thankful to the manager (Laurent Blanc). From the beginning he was clear where he wanted to play me and has never changed his mind,” Di Maria added.“He has given me total freedom to move where I need to move and I’m very happy here. It wasn’t the case over there (United).” Angel Di Maria is expected to miss PSG’s home match with Nice 1
Minister of National Security, Hon. Peter Bunting, has announced that the government is working to reconcile the databases of the Tax Administration of Jamaica (TAJ) and the island’s courts, to add all traffic tickets that have been paid on both systems. Speaking at a press briefing at the Ministry’s offices in New Kingston on Wednesday (January 16), Mr. Bunting said that the consolidation process, which is now in progress, should be completed by February. He said at that time, Cabinet will decide on whether there will be an extension of the previous amnesty. “All those 127,000 tickets that were settled during the amnesty, we’re going to upload those (to the database). We have a huge project going on where we’ve gone to the courts and we’re going through their manual-based system and we’re doing the data entry to bring the tickets settled at the courts onto the electronic database,” he said. The Security Minister said that the final stage of the process is to resolve those cases involving persons who say they have paid their tickets, but those tickets are still seen on the system as unpaid. “We will be setting up machinery to resolve those tickets that are being contested. When that is complete, Cabinet will decide, after looking at all the data, whether it makes sense to have another brief amnesty or whether we can go forward with making the payments in the courts, as what is in place now,” he said. Mr. Bunting also said that he has asked Head of the Traffic Department, Superintendent Radcliffe Lewis, to refrain from enforcing arrest warrants on those tickets until “we are confident that all the payments are reflected and brought current”.
Aug 9 • What a security researcher learned from monitoring traffic at Defcon Black Hat Defcon All the different Android versions through the years Aug 10 • That 4G hotspot could be a hotbed for hackers Stone, who discussed her research at the Black Hat cybersecurity conference in Las Vegas on Thursday, sees preinstalled malware as a threat that security researchers aren’t often focused on, since attention is usually directed toward malware that victims download on their own. But unlike downloaded malware, preinstalled malware is harder to find and even more difficult to get rid of. “If malware or security issues can make its way as a preinstalled app, then the damage it can do is greater, and that’s why we need so much reviewing, auditing and analysis,” she said. Because Apple has full control over its iPhone, preinstalled malware isn’t much of a concern for iOS, or the App Store. Many of the preinstalled harmful apps pop up after a malicious actor tricks phone makers into including their software on their devices. Android’s security team discovered two major malware campaigns hidden in preinstalled apps over the last three years, one called Chamois and the other called Triada. Together, they infected tens of millions of low-budget Android devices from the moment they were shipped out. Google did not specify which phones were affected.At Black Hat, Stone detailed three new case studies on preinstalled apps that posed threats to Android devices, though it’s unclear whether the apps’ creators had malicious intent. They affected millions of devices and turned off Google Play Protect, spied on people’s web activity and allowed potential hackers to run code remotely, Stone said. Case studies Stone discussed two cases where the preinstalled “malware” were accidents, but still presented a security threat for millions of people. Up to 225 device makers had apps with code that allowed for remote code execution. These apps opened a window that would allow anyone online to connect to it, and once it did, the person would have complete control. This affected 6 million devices, but was fixed within a month, Stone said. In the second case, consumer and commercial conglomerate Honeywell had vulnerabilities preinstalled on Android devices controlling its industrial control systems. Any apps on the Android devices that Honeywell was using had extended privileges, so a potential attacker could have abused that security flaw and stolen passwords and documents. The company disclosed that vulnerability last September. In another case study, the Android security team found a preinstalled app that turned off Google Play Protect, which it fixed last November. Stone also described a preinstalled app that took detailed logs of people’s web activities, which Google considers spyware. Black Hat Defcon reading • Android malware that comes preinstalled is a massive threat Aug 11 • DARPA’s $10 million voting machine couldn’t be hacked at Defcon (for the wrong reasons) Mobile Security 2 Share your voice When malware comes preinstalled on Android devices, it’s much harder to remove, Google’s researchers said. Omar Marques/SOPA Images/LightRocket via Getty Images Keeping your Android device safe from malware is difficult enough as it is — but it’s an entirely different threat when the harmful apps come with your device. Android’s open-source operating system allows for more affordable alternatives for millions of people, but it also opens the door for hackers to sneak in prepackaged malware.Preinstalled malware had been discovered on more than 7.4 million Android devices, which had the ability to take over devices and download apps in the background while committing ad fraud, researchers working for Google found. While major Android partners like Samsung or LG, as well as Google’s own Pixel devices, are likely safe from these kinds of threats, budget phone makers who rely on third-party software to save a few bucks could be vulnerable. Attackers offer genuine services, and hide the malware in the apps they provide, according to Maddie Stone, a security researcher on Google’s Project Zero and previously a tech lead on the Android Security team. “If malware or security issues can make its way as a preinstalled app, then the damage it can do is greater, and that’s why we need so much reviewing, auditing and analysis/” Maddie Stone, a security researcher on Google’s Project Zero Comments Tags Aug 10 • Those robocall blocker apps are hanging up on your privacy See All Preinstalled vs. downloaded malwareAll malware might seem the same to you, but when it’s preinstalled, there are a few key differences that make it a more dangerous threat. Since they’re approved and installed by the phone makers, antivirus programs don’t flag them as harmful, even if an app is behaving exactly like malware would. These apps also have escalated permissions compared to downloaded malware, and can’t be removed unless the phone makers send a security update, Stone said. Google Play Protect can disable the malicious app, but it can’t remove it completely. In 2018, the Android Security team reviewed builds from about 1,000 different phone makers to make sure there weren’t any preinstalled malware packaged in with the devices.”I put a lot of my own time and resources into finding it then versus after the fact to identify all of these issues before they ever go out to users,” Stone said. “We want to make sure no one is infected because we talk about how hard it is to remove after the fact.”In March 2018, the Chamois botnet had infected 7.4 million devices. By July, there were about 700,000 devices still infected, Stone said. Sometimes, those security updates never arrive, or people don’t download them.Because these apps are preinstalled, they can often remain hidden without an icon, leaving people unaware that they’re even affected. While hackers try to get victims to download malware, with preinstalled apps, attackers just have to trick the phone makers. “If you are able to infiltrate the supply chain out of the box, then you already have as many infected users as how many devices they sell,” Stone said. “That’s why it’s a scarier prospect and I really hope more researchers join us in vetting these processes.” • 17 Photos
Citation: Researchers simulate information signaling between cells (2015, October 5) retrieved 18 August 2019 from https://phys.org/news/2015-10-simulate-cells.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. (Phys.org)—Many natural systems are described by dynamics of traveling wavefronts. Sharp traveling fronts are employed in countless phenomena, including fluid convection, chemical reactions, and cellular phenomena. Living systems use front propagation encoded in biochemical reactions to communicate and perform computations, but these dynamics are difficult to study in three dimensions (i.e., in vivo). Thus, to understand how propagating gene expression fronts work in complex living systems, it is important to study how they work in minimal systems. Artificial cells act like the real thing More information: “Propagating gene expression fronts in a one-dimensional coupled system of artificial cells.” Nature Physics (2015) DOI: 10.1038/nphys3469AbstractLiving systems employ front propagation and spatiotemporal patterns encoded in biochemical reactions for communication, self-organization and computation. Emulating such dynamics in minimal systems is important for understanding physical principles in living cells and in vitro. Here, we report a one-dimensional array of DNA compartments in a silicon chip as a coupled system of artificial cells, offering the means to implement reaction–diffusion dynamics by integrated genetic circuits and chip geometry. Using a bistable circuit we programmed a front of protein synthesis propagating in the array as a cascade of signal amplification and short-range diffusion. The front velocity is maximal at a saddle-node bifurcation from a bistable regime with travelling fronts to a monostable regime that is spatially homogeneous. Near the bifurcation the system exhibits large variability between compartments, providing a possible mechanism for population diversity. This demonstrates that on-chip integrated gene circuits are dynamical systems driving spatiotemporal patterns, cellular variability and symmetry breaking. Explore further © 2015 Phys.org Journal information: Nature Physics A group of researchers in Israel and the United States report in Nature Physics the results of a study of a one-dimensional array of artificial cells in a silicon chip—in essence, a system of coupled cells in which the researchers could implement reaction-diffusion effects and study how they propagate among cells.Artificial cells?Artificial cells are engineered systems of various kinds that simulate a number of functions of biological cells. In this case, the array of cells consists of 15 compartments inside which the researchers patterned gene circuits. The compartments simulate the microencapsulation of the biological membranes of cells, separating the internal cellular mechanisms from other “cells” while allowing the exchange of small molecules.Carved into a silicon substrate, the compartments were fed by a main flow channel and interconnected by fork-shaped capillaries. Cell extract from Escherichia coli was fed continuously through the main channel. The researchers were interested in how biological multicellular systems use traveling wavefronts to communicate. Signals dissipate over short distances within a medium, so cells accomplish long-range transmission of information by consecutive local cell-to-cell interactions. In living systems, the transmission models are too complex to study, but this isolated array of artificial cells revealed interesting dynamics likely applicable to the study of actual multicellular systems.Though front propagation has been studied in the past, yielding results that have applications in science and industry, the authors note that this is the first time anyone has created a synthetic, spatially coupled cellular system capable of long-range cell-to-cell communication. The first compartment was patterned with a small amount of starter protein construct, and as the medium flowed through the channels, the researchers found that the DNA starter initiated diffusion of the activator to the neighboring compartment. This created an autocatalytic reaction in which the neighboring compartment created a new source of activator. The researchers characterized expression-diffusion dynamics by measuring the timescales between the diffusion of proteins along the capillaries, which occurred over minutes, and the gene expression dynamics in the compartments, which changed over hours. In essence, the researchers created a system of autocatalyzing protein synthesis in which the activator signal cascaded through the compartments, which amplified it and diffused it to neighboring compartments. The authors write, “The spatial organization of DNA circuits together with short interaction length, set by the array geometry, will allow integrating long-range signaling with local information processing reactions based on gene expression, in analogy to multicellular systems, electronic circuits, and neural networks.”
Kolkata: A thundershower accompanied by lightning hit four South Bengal districts and some parts of the city on Sunday morning saving residents from the hot and humid condition.The rain has brought down the temperature by a few notches. Districts like North 24-Parganas, South 24-Parganas, Nadia and Murshidabad received moderate to heavy rainfall coupled with lightning from Sunday morning.The rain lasted for nearly two hours and the city remained cloudy. As the day progressed, the city dwellers witnessed light to moderate rainfall. Also Read – Rain batters Kolkata, cripples normal lifeA strong wind was blowing at 40-60 km/hour in some parts of South Bengal on Sunday.The regional meteorological centre at Alipore has predicted a possibility of thunderstorm in some South Bengal districts on Monday as strong moisture-laden southwesterly wind would blow in the area, creating a favourable environment for a storm.The city may also receive scattered rainfall in the next 24 hours as predicted by the weather office. It may be mentioned that vehicular movement on various stretches of the city remained slow following the rain. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedAccording to Alipore MeT office, there may be heavy rainfall in some North Bengal districts in the next 24 hours.It may be mentioned that the city witnessed moderate to heavy rainfall a few days ago due to cyclonic circulation that was earlier hovering over Gangetic Bengal.As a result, some parts of the city and adjoining areas witnessed scattered rainfall for the past few days. Situation was further intensified in South Bengal after a low pressure trough was formed over Bay of Bengal.According to a weather expert, the formation of thunder cloud over Gangetic plains has contributed to the rains.Multiple thunderstorms may swept through some parts of South Bengal till Monday.